My Daily Longevity Stack — A Cellular Approach to Health

 

Every day, I focus on optimising my energy, cellular health, and long-term vitality through a carefully designed supplement protocol that supports mitochondrial function, detoxification, and cellular renewal. As a biohacker, I take a data-driven approach, integrating both nutraceuticals and prescribed therapies under ongoing review. Below is a breakdown of my daily longevity stack, including how each component fits into my broader strategy for optimising health at the cellular level.

Remember, I’m a biohacker — not your everyday Joe. This isn’t just a hobby; it’s my passion and my life’s work. I experiment, I track, I analyse, and I optimise. Every compound I take has a purpose, every choice is intentional. This stack isn’t about chasing fads — it’s about pushing the boundaries of what’s possible for health, performance, and longevity.

 

Disclaimer:
‘The information shared in this article reflects my personal perspective and routine. It is intended for educational purposes only and should not be interpreted as medical advice or a recommendation for others to follow. Always consult a qualified healthcare professional before making changes to your supplement, medication, or lifestyle regimen.’

 

 

1. Cellular Foundation Builder

L-Glycine — Supports collagen, sleep, detoxification, and glutathione production.
Taurine — Enhances mitochondrial function, supports heart health, and promotes calm energy.
Creatine Monohydrate — Increases cellular energy (ATP) production, supports muscle strength, and enhances cognitive function.
Collagen Hydrolysate — Provides essential amino acids for connective tissue repair, skin elasticity, joint strength, and gut integrity.

These foundational compounds form the backbone of my cellular and structural health strategy. Glycine maintains DNA integrity and supports sleep quality, while taurine improves mitochondrial performance and cellular regulation. Creatine adds direct ATP energy support for muscles and neurons, and Collagen Hydrolysate provides the raw materials for structural protein synthesis throughout the body.

2. Cellular Protection (Senolytics)

Trans-Resveratrol — Activates longevity genes (SIRT1), supports cardiovascular health.
Quercetin — Helps clear senescent (aged) cells and reduces inflammation.
Fisetin — One of the most potent natural senolytics; promotes cellular rejuvenation.

These compounds work together to remove dysfunctional cells, reduce inflammation, and protect healthy tissue — helping the body renew itself naturally. I typically use senolytics intermittently to mimic fasting-induced autophagy.

3. NAD+ & Mitochondrial Support

NMN — Boosts NAD+ for cellular energy and DNA repair.
PQQ — Stimulates the growth of new mitochondria.
CoQ10 — Improves mitochondrial efficiency and heart function.
Liposomal Glutathione — Provides direct antioxidant protection, supports liver detoxification, and enhances cellular redox balance.
Methylene Blue (pulsed) — I occasionally pulse low-dose methylene blue to enhance mitochondrial efficiency and mental clarity, cycling it intermittently to maintain redox balance.

This set keeps my cells energised and youthful. NMN raises NAD+ — the key molecule for energy metabolism — while PQQ promotes the creation of new mitochondria. CoQ10 supports energy transfer and cardiovascular performance. Liposomal glutathione enhances detoxification and reduces oxidative stress at the cellular level. Methylene blue adds a nootropic, mitochondrial support element that complements these mechanisms.

4. Metabolic & AMPK Activation

Metformin — A prescription biguanide that improves insulin sensitivity, lowers hepatic glucose output, and activates AMPK signalling for enhanced metabolic resilience and potential longevity benefits.
Dihydroberberine — Enhances insulin sensitivity and activates AMPK for better fat metabolism.
Astaxanthin — One of the most potent antioxidants for skin, eyes, and cellular protection, offering advanced anti-inflammatory and mitochondrial support benefits.

These compounds collectively regulate glucose metabolism, support mitochondrial function, and promote metabolic flexibility — central mechanisms in ageing and chronic disease prevention.

5. Cellular Renewal & Autophagy

Spermidine — Triggers autophagy (cellular recycling) and supports heart health.
Urolithin A — Enhances mitophagy (the renewal of old mitochondria) and muscle strength.

Together, these compounds encourage the body’s natural clean-up and repair processes, crucial for healthy ageing.

6. Foundational Vitamins & Minerals

I take a complete micronutrient complex daily — all in bioavailable forms — covering vitamins A, C, D3, E, K1 + K2 (MK-7), and the full methylated B-vitamin spectrum (including folate and methylcobalamin B12).
Key minerals include magnesium (glycinate), zinc (citrate), selenium (selenomethionine), iodine (potassium iodide), calcium (citrate/phosphate), and potassium (citrate).

These nutrients support detoxification, methylation, hormone balance, bone density, and energy metabolism — the fundamentals of optimal physiology.

7. Superfoods, Greens & Phytonutrients

I use a concentrated blend of antioxidant-rich fruits, greens, and herbs — including acai, blueberry, beetroot, green tea, turmeric, milk thistle, and pomegranate — to provide additional polyphenols, liver support, and immune modulation.

This plant matrix amplifies antioxidant defence, improves circulation, and supports natural detoxification.

8. Gut & Microbiome Health

Probiotics: Bacillus coagulans + Bacillus subtilis.
Postbiotic: Lactobacillus casei 327.
Prebiotics: Inulin + Guar fibre.
Green Banana–Derived Resistant Starch — A natural prebiotic that feeds beneficial gut bacteria, supports butyrate production, and improves metabolic flexibility.

These maintain digestive balance, support the gut lining, and enhance nutrient absorption. A balanced microbiome has systemic effects — including on immune regulation and mental clarity.

9. Immune & Inflammatory Support

Oil of Oregano — A natural antimicrobial and immune-supportive oil that helps defend against pathogens and supports respiratory health.
Black Seed Oil — Renowned for its broad anti-inflammatory properties and support for immune balance, cardiovascular health, and cellular repair.

These two oils provide potent natural defence and help maintain inflammatory balance throughout the body.

10. Joint & Muscle Vitality

MSM — Supports joint comfort, collagen production, and tissue flexibility.
HMB — A metabolite of leucine that helps preserve lean muscle mass, reduce muscle breakdown, and enhance recovery, particularly during calorie restriction or ageing.

I find this combination particularly beneficial for maintaining strength, reducing stiffness, and supporting tissue repair following training or long workdays.

11. Amino Acids & Regeneration

L-Citrulline, L-Leucine, L-Isoleucine, L-Valine, L-Lysine, L-Proline, L-Glutamine, Taurine, Glycine, Creatine, Collagen Hydrolysate, HMB — Together these support muscle recovery, collagen repair, and energy metabolism.

They form a foundational network for recovery, growth, and structural integrity.

Advanced Regeneration

Wharton’s Jelly Exosomes
Regenerative extracellular vesicles derived from umbilical Wharton’s Jelly — rich in growth factors, cytokines, and microRNAs that signal repair, modulate inflammation, and rejuvenate tissue at the cellular level. They represent the cutting edge of regenerative medicine, facilitating intercellular communication and unlocking new layers of biological repair potential.

12. Adaptogens & Super Mushrooms

Ashwagandha, Rhodiola, American Ginseng, Andrographis — Adaptogens for stress resilience and energy balance.
Lion’s Mane, Reishi, Chaga — Support cognitive function, immunity, and longevity.

These compounds help stabilise stress hormones and improve focus, mental clarity, and immune tone.

13. Electrolytes & Hydration

Magnesium, Calcium, Potassium, Phosphorus (glycinate/citrate forms) — Maintain electrolyte balance, muscle function, and hydration, especially during fasting or exercise.

14. Growth & Recovery Modulation

MK-677 (Ibutamoren) — I periodically cycle MK-677 to support natural growth hormone release, improve recovery, and enhance sleep quality. It’s a key part of my experimentation around tissue regeneration and longevity signalling.

My Dosing Rhythm

• Morning: Vitamins/minerals, NMN, PQQ, CoQ10, Metformin, Dihydroberberine, Liposomal Glutathione, Methylene Blue (pulsed), Probiotics, Adaptogens.
• Midday: Greens + Polyphenol blend.
• Pre-Workout: Creatine, Collagen Hydrolysate, HMB, and L-Citrulline.
• Evening: Metformin, Glycine, Taurine, Magnesium glycinate, MSM, and additional Liposomal Glutathione for recovery and deep sleep.
• Intermittent Senolytics: 1–2 days weekly or 2 consecutive days per month.

 

Closing Thoughts

This protocol reflects a systems-biology approach — combining molecular nutrition, lifestyle optimisation, and pharmacological longevity interventions. Every ingredient serves a targeted role in energy metabolism, detoxification, repair, or resilience.

The goal isn’t merely lifespan — it’s healthspan: maintaining the vitality, clarity, and capability to thrive through every decade.

 

Robert Van der Moigg – Founder
Life X DNA™