Is Inflammation Genetic? – Exploring Your DNA’s Role in Chronic Inflammation

We look at over 900,000 SNP’s and use the latest AI powered software to analyse over 80 million variants that significantly influence your health.

If you experience persistent inflammation without a clear cause, your genes may be part of the explanation. Some people are genetically predisposed to a stronger or longer-lasting immune response, even in the absence of illness or injury.

At Life X DNA, we include analysis of inflammation-related genes as part of our comprehensive DNA testing kits – available throughout Australia and New Zealand. These reports provide insight into immune activity, detox function and oxidative stress recovery.

Genetic Methylation Tests Melbourne

Why Do I Have Inflammation for No Reason?

Low-grade inflammation that persists for weeks or months may be driven by internal imbalances rather than an active infection or injury.

In some cases, this may be linked to inherited variation in:

  • Cytokine signalling (immune system “messenger” chemicals)
  • Oxidative stress and antioxidant response genes
  • Detoxification efficiency
  • Gut barrier integrity or food sensitivity genes

These inherited traits can affect how quickly your body resolves inflammation and whether small stressors trigger an outsized immune response.

Genes Linked to Chronic Inflammation

Life X DNA reports include analysis of several inflammation-relevant genes, including:

  • IL6, TNF, IL10 – cytokine genes that regulate inflammation signalling
  • NQO1, SOD2 – antioxidant response genes that reduce oxidative damage
  • GSTM1, GSTP1 – detox genes that help neutralise toxins
  • DAO, FUT2 – genes that affect histamine breakdown and gut sensitivity

Variations in these pathways may contribute to inflammatory load or immune system overactivity, particularly when combined with environmental triggers.

MTHFR Tests Melbourne
DNA Health Tests Melbourne

Genetic Testing for Inflammation and Immune Sensitivity

Our testing does not diagnose inflammatory conditions, but it may help you understand:

  • How your immune system reacts to perceived stress
  • Whether detox or antioxidant pathways may need support
  • Which genetic variants may be influencing your baseline inflammation

The report is structured to support personal decision-making in consultation with a health practitioner – not to replace clinical testing.

What’s Covered in Your Life X DNA Report

Your report includes insights related to:

  • Pro- and anti-inflammatory cytokine genes
  • Histamine breakdown and immune overactivity
  • Oxidative stress response and detoxification
  • Gene-environment interactions that may influence chronic inflammation

All results are delivered via a secure online portal, and your sample is processed in our ISO-certified Perth lab.

Genetic Methylation Tests New Zealand

Available in Australia and New Zealand

Life X DNA test kits are shipped AU/NZ-wide with return shipping included. Your results are private, detailed, and structured to support personalised wellness strategies.

FAQs – Inflammation and Genetics

Yes. Genes involved in immune signalling, antioxidant function, and detox may influence how your body manages inflammation over time.

Chronic low-grade inflammation may result from immune overactivation, poor detox or slow stress recovery – all of which can be affected by genetics.

We analyse IL6, TNF, IL10, NQO1, GSTM1, SOD2, DAO and others related to immune function and inflammation pathways.

Order your Life X DNA kit online, collect your cheek swab at home, and return it to our Perth-based lab. Results are delivered securely through our digital portal.